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Puberty, the menstrual cycle and contraception – GCSE Combined Science Biology

Foundation and Higher · Grade 6

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The hormones of puberty and the menstrual cycle, how contraception works, and how fertility can be treated.

Objectives

Specification references this topic covers: AQA 4.5.3; Edexcel B7.4, B7.5, B7.6, B7.7, B7.8.

Puberty, the menstrual cycle and contraception explained

Start here

Hormones are chemical messengers. A gland makes them and sends them in the blood to another part of the body. Reproductive hormones control how the body changes in puberty and how the menstrual cycle works.

This matters because it is part of how every human body develops. Understanding it also helps people make informed choices about contraception and fertility.

By the end you will be able to name the main reproductive hormones and what they do. You will describe the stages of the menstrual cycle. You will also compare contraception methods and explain how fertility can be treated.

Puberty

Puberty is the stage when the body becomes able to reproduce. It starts because hormones rise. The pituitary gland, a small gland in the brain, helps to control them.

In males the testes make testosterone, the main male reproductive hormone. It causes secondary sexual characteristics, such as a deeper voice and body hair. It also stimulates sperm production.

In females the ovaries make oestrogen, the main female reproductive hormone. It causes breast development and starts the menstrual cycle. The cycle includes the release of eggs from the ovaries.

The menstrual cycle

The menstrual cycle lasts about 28 days. It prepares the body for a possible pregnancy. The uterus is the womb, where a baby grows. Its lining is like a bed made up for a guest.

On days 1 to 5 the lining breaks down and leaves the body. This is menstruation. The lining then builds up again.

Around day 14 an egg is released from an ovary. This is ovulation. The lining stays thick until about day 28. If no egg is fertilised, the lining breaks down and a new cycle starts.

The four hormones

Four hormones control the cycle. They pass messages like runners in a relay. FSH comes from the pituitary gland. It matures an egg in an ovary and makes the ovary release oestrogen.

Oestrogen builds up the lining of the uterus. It also tells the pituitary to release LH. LH causes ovulation. Progesterone is made by the empty follicle in the ovary after ovulation. It maintains the lining.

High oestrogen and progesterone stop FSH being released. So no more eggs mature.

Hormonal contraception

Contraception prevents pregnancy. Some methods use hormones, which are chemical messengers.

The contraceptive pill contains oestrogen and progesterone. They stop FSH being released, so no eggs mature. If there is no egg, there is nothing to fertilise. Think of it as keeping the starting signal for egg growth switched off. The implant, the patch and the injection also use hormones. The implant sits under the skin, and the patch sticks onto it.

Hormonal methods are very effective. But they can cause side effects, and they do not protect against infections.

Other types of contraception

Barrier methods stop sperm reaching the egg. Condoms and diaphragms are examples. Condoms also reduce the risk of sexually transmitted infections. A diaphragm is a soft cap that covers the cervix, which is the entrance to the uterus.

An intrauterine device, or coil, stops an embryo implanting in the uterus. Spermicides are chemicals that kill sperm.

Surgical methods, such as sterilisation, are permanent. Abstinence means not having sex near ovulation. Each method has good and bad points.

Fertility treatments

Some women do not release eggs. They can take FSH and LH, which help eggs mature and be released.

In vitro fertilisation, or IVF, is another treatment. Eggs are collected after the woman takes FSH and LH. They are fertilised with sperm in a laboratory. The embryos grow for a few days, and one or two are put into the uterus.

IVF can give a baby to couples who cannot conceive. But it has a low success rate. It is stressful and expensive. It can also cause multiple births, which are risky for the mother and babies.

Clomifene therapy is another treatment. Clomifene is a drug that is taken as a tablet. It stimulates the body to release more FSH and LH, so that eggs mature and are released. It is used for women whose eggs do not mature or are not released.

Recap

Testosterone comes from the testes. Oestrogen comes from the ovaries.

Menstruation is days 1 to 5. Ovulation is about day 14. The cycle is about 28 days.

FSH matures the egg. Oestrogen builds the lining. LH causes ovulation. Progesterone maintains the lining.

Contraception can be hormonal, barrier, a coil, spermicide, surgical or abstinence. IVF can help couples who cannot conceive.

Key points

Worked examples

Example 1

Name the hormone that causes the lining of the uterus to grow.

  1. The lining is built up in the first half of the cycle.
  2. The hormone is made by the ovary.
  3. The hormone is oestrogen.

Answer: oestrogen

Common slips
  • Slip: FSH FSH makes the egg mature.
  • Slip: LH LH causes ovulation.
  • Slip: testosterone Testosterone is a male hormone.

Example 2

Explain how the contraceptive pill prevents pregnancy.

  1. The pill contains oestrogen and progesterone.
  2. These hormones inhibit the release of FSH.
  3. So eggs do not mature, and there is no ovulation.

Answer: It stops FSH being made so eggs do not mature

Common slips
  • Slip: It kills sperm. That is a spermicide, not the pill.
  • Slip: It blocks the vagina. That is a barrier method.
  • Slip: It makes LH rise. The pill stops FSH, so eggs do not mature.

Example 3

Explain how FSH, oestrogen and LH control the first half of the menstrual cycle.

  1. FSH from the pituitary makes an egg mature and stimulates the ovary to release oestrogen.
  2. Oestrogen makes the lining of the uterus grow and stimulates the pituitary to release LH.
  3. A rise in LH then causes ovulation around day 14.

Answer: FSH matures the egg and causes oestrogen release, oestrogen builds the lining and triggers LH, and LH causes ovulation

Common slips
  • Slip: LH makes the egg mature. FSH makes it mature. LH causes ovulation.
  • Slip: Progesterone causes ovulation. Progesterone maintains the lining after ovulation.
  • Slip: Oestrogen is made by the pituitary. Oestrogen is made in the ovary.

Questions and answers

Puberty, the menstrual cycle and contraception practice questions for GCSE Combined Science Biology. Try each one, then open the answer. Easy questions come first.

Question 1 Easy

Name the male sex hormone.

Show answer

Answer: testosterone

  1. It is made in the testes.
  2. It is testosterone.

Question 2 Easy

Name the female sex hormone made in the ovary.

Show answer

Answer: oestrogen

  1. It builds the uterus lining.
  2. It is oestrogen.

Question 3 Easy

What is the release of an egg from the ovary called?

Show answer

Answer: ovulation

  1. It happens near day 14.
  2. It is ovulation.

Question 4 Easy

What is the loss of the uterus lining called?

Show answer

Answer: menstruation

  1. It happens on days 1 to 5.
  2. It is menstruation.

Question 5 Medium

Which hormone causes ovulation?

Show answer

Answer: LH

  1. It is made by the pituitary.
  2. It is LH.

Question 6 Medium

Which hormone causes an egg to mature in the ovary?

Show answer

Answer: FSH

  1. It is made by the pituitary.
  2. It is FSH.

Question 7 Medium

Which hormone maintains the lining of the uterus after ovulation?

Show answer

Answer: progesterone

  1. It is made by the empty follicle.
  2. It is progesterone.

Question 8 Medium

Which gland makes FSH and LH?

Show answer

Answer: pituitary

  1. It is the master gland.
  2. It is the pituitary.

Exam-style questions

Longer questions in the style of a written paper, with the marking points. These are Yumio practice questions.

Exam-style question 14 marks

(a) Name the hormone that causes ovulation. [1 mark] (b) State where this hormone is made. [1 mark] (c) Explain the role of progesterone in the menstrual cycle. [2 marks]

Show answer and marking points

Answer: (a) LH (b) the pituitary gland (c) progesterone maintains the lining of the uterus and helps keep it thick for a fertilised egg, and inhibits FSH

  • (a) LH (1)
  • (b) pituitary gland (1)
  • (c) maintains the lining of the uterus (1)
  • (c) it is made by the ovary after ovulation or it inhibits FSH (1)

Exam-style question 24 marks

Evaluate the use of the contraceptive pill compared with condoms. [4 marks]

Show answer and marking points

Answer: The pill is very effective at preventing pregnancy because it stops FSH so no eggs mature. It does not protect against sexually transmitted infections and can have side effects. Condoms are a barrier, so they stop sperm and protect against infection, but they can split or be used incorrectly, so they are a little less effective.

  • the pill is very effective at preventing pregnancy (1)
  • the pill does not protect against infection, or has side effects (1)
  • condoms protect against sexually transmitted infections (1)
  • condoms can fail through splitting or incorrect use, so are less effective alone (1)

Common mistakes

  1. Saying FSH and LH are made in the ovary

    FSH and LH are made by the pituitary gland.

  2. Saying progesterone causes ovulation

    LH causes ovulation. Progesterone maintains the uterus lining.

  3. Saying all contraception protects against infection

    Only condoms also reduce the risk of sexually transmitted infections.

  4. Saying the cycle always lasts exactly 28 days

    The cycle length varies. 28 days is an average for exam purposes.

Questions students ask

Is Puberty, the menstrual cycle and contraception on the Foundation or Higher tier?

Puberty, the menstrual cycle and contraception is on both Foundation and Higher papers for GCSE Combined Science Biology, aimed at around grade 6.

What is a common mistake on Puberty, the menstrual cycle and contraception?

Saying FSH and LH are made in the ovary. FSH and LH are made by the pituitary gland.

Where are the answers to the Puberty, the menstrual cycle and contraception questions?

Open Show answer under each question on this page. The questions are Yumio practice questions, not past exam questions.

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