Skip to content

Paper Together: sit a paper in a room with your friends.See how it works

Blood – GCSE Combined Science Biology

Foundation and Higher · Grade 4

Jump to the questions and answers

Plasma, red blood cells, white blood cells and platelets, and how each is adapted for its job.

Objectives

Specification references this topic covers: AQA 4.2.2, 4.3.1; Edexcel B8.1, B8.6.

Blood explained

Start here

Blood is the red liquid that moves around your body. It is a tissue, which means a group of different cells and parts working together. It has four parts: plasma, red blood cells, white blood cells and platelets.

It matters because blood is the body's delivery and defence system. It takes oxygen and food to every cell, carries waste away, and helps to fight disease. Without it your cells would stop working.

By the end you will be able to name the four parts and say what each one does. You will also explain how red blood cells are built to carry oxygen.

Plasma

Plasma is the pale yellow liquid part of blood. Most of it is water. The other three parts are carried along in it, and so are many dissolved substances.

Think of plasma as the road that all the deliveries travel on. It carries digested food, such as glucose, from the gut to the cells. It carries carbon dioxide from the organs to the lungs. It carries urea, a waste made in the liver, to the kidneys.

Plasma also carries hormones, which are chemical messages, and it spreads heat around the body.

Red blood cells and haemoglobin

Red blood cells carry oxygen from the lungs to every cell in the body. Cells need oxygen to release energy from food.

Each red blood cell is full of haemoglobin. This is a red protein that joins with oxygen in the lungs to make oxyhaemoglobin. Think of haemoglobin as a tiny delivery van that picks up oxygen.

In the body tissues the haemoglobin lets go of the oxygen, and the oxygen passes into the cells. Haemoglobin is what makes blood look red.

How red blood cells are adapted

An adaptation is a feature that helps a cell do its job. Red blood cells have no nucleus. The nucleus is the part of a cell that holds its genes. Leaving it out makes more room for haemoglobin.

Each cell is a biconcave disc, which means it is dented in on both sides. This gives it a large surface area, so oxygen can get in and out quickly.

The cells are also small and flexible. This lets them squeeze through capillaries, which are the narrowest blood vessels.

White blood cells and phagocytes

White blood cells are part of the immune system, which defends the body. They fight pathogens. A pathogen is a microorganism that causes disease, such as a harmful bacterium or virus.

Some white blood cells are phagocytes. A phagocyte engulfs a pathogen, which means it wraps around it and takes it in. It then digests the pathogen and destroys it.

Unlike red blood cells, white blood cells have a nucleus. You have far fewer of them than red blood cells.

Antibodies and antitoxins

Other white blood cells are lymphocytes. They make antibodies, which are chemicals that destroy one particular kind of pathogen. Some also make antitoxins. These neutralise the poisons that pathogens release.

A football team is a helpful picture. Phagocytes are the defenders who tackle anything that should not be on the pitch. Lymphocytes are the planners, making antibodies aimed at one particular attacker.

When you have an infection, your body makes more white blood cells to fight it.

Platelets

Platelets are small fragments of cells. They have no nucleus, so they are not whole cells. Their job is to help the blood to clot.

To clot means to change from a runny liquid into a thick, sticky seal. When you cut yourself, platelets gather at the wound and a clot forms. The clot then dries into a scab.

The scab stops blood escaping and keeps microbes out while the skin heals. Think of it as a plaster that your body makes for itself. Without platelets, even a small cut would keep bleeding.

Recap

Blood has four parts: plasma, red blood cells, white blood cells and platelets.

Plasma is the liquid. It carries digested food, carbon dioxide, urea, hormones and heat.

Red blood cells carry oxygen using haemoglobin. They have no nucleus and are biconcave.

White blood cells fight pathogens. Platelets help the blood to clot.

Key points

Worked examples

Example 1

Name the red substance in red blood cells that carries oxygen.

  1. Red blood cells carry oxygen.
  2. The protein that joins to oxygen is in the cell.
  3. It is haemoglobin.

Answer: haemoglobin

Common slips
  • Slip: plasma Plasma is the liquid part of the blood.
  • Slip: platelets Platelets help blood to clot.
  • Slip: chlorophyll Chlorophyll is green and found in plants.

Example 2

Give two ways in which a red blood cell is adapted to carry oxygen.

  1. It has no nucleus, so there is more room for haemoglobin.
  2. It is a biconcave disc, which gives a large surface area.
  3. Haemoglobin joins with oxygen to carry it.

Answer: no nucleus and a biconcave shape

Common slips
  • Slip: It has a large nucleus. Red blood cells have no nucleus.
  • Slip: It has a cell wall. Animal cells such as red blood cells have no cell wall.
  • Slip: It is round and flat so it clots. Clotting is the job of platelets.

Example 3

A person has a cut. Describe the roles of platelets and white blood cells in the body’s response.

  1. Platelets cause the blood to clot, forming a scab that stops blood loss.
  2. The scab keeps pathogens out.
  3. White blood cells inside engulf pathogens or make antibodies against them.

Answer: Platelets clot the blood to seal the cut and white blood cells engulf pathogens or make antibodies

Common slips
  • Slip: Platelets kill the pathogens. Platelets clot the blood. White blood cells attack pathogens.
  • Slip: White blood cells make the scab. The scab is made by platelets.
  • Slip: Red blood cells heal the cut. They carry oxygen. They do not seal wounds.

Questions and answers

Blood practice questions for GCSE Combined Science Biology. Try each one, then open the answer. Easy questions come first.

Question 1 Easy

Name the liquid part of blood.

Show answer

Answer: plasma

  1. It carries the cells and dissolved substances.
  2. It is plasma.

Question 2 Easy

Which blood cells carry oxygen?

Show answer

Answer: red blood cells

  1. They contain haemoglobin.
  2. They are red blood cells.

Question 3 Easy

Which part of blood helps it to clot?

Show answer

Answer: platelets

  1. They seal wounds.
  2. They are platelets.

Question 4 Easy

Name the type of cell that makes antibodies.

Show answer

Answer: white blood cell

  1. Antibodies are part of the immune system.
  2. White blood cells make them.

Question 5 Easy

Is plasma a solid, a liquid or a gas?

Show answer

Answer: liquid

  1. Plasma is the part that the cells float in.
  2. It is a liquid.

Question 6 Easy

What name is given to microorganisms that cause disease?

Show answer

Answer: pathogens

  1. White blood cells fight these.
  2. They are pathogens.

Question 7 Medium

Which red protein carries oxygen in the blood?

Show answer

Answer: haemoglobin

  1. It is found in red blood cells.
  2. It is haemoglobin.

Question 8 Medium

Name the white blood cells that engulf pathogens.

Show answer

Answer: phagocytes

  1. They take in and digest pathogens.
  2. They are phagocytes.

Exam-style questions

Longer questions in the style of a written paper, with the marking points. These are Yumio practice questions.

Exam-style question 14 marks

(a) Describe the function of platelets. [1 mark] (b) Explain how the structure of a red blood cell helps it to carry oxygen. [3 marks]

Show answer and marking points

Answer: (a) they help the blood to clot (b) haemoglobin joins with oxygen, no nucleus gives more room for haemoglobin, and the biconcave shape gives a large surface area

  • (a) help the blood to clot (1)
  • (b) contains haemoglobin, which joins with oxygen (1)
  • (b) no nucleus, so more room for haemoglobin (1)
  • (b) biconcave shape gives a large surface area (1)

Exam-style question 24 marks

Explain the roles of plasma and white blood cells in the blood. [4 marks]

Show answer and marking points

Answer: Plasma transports carbon dioxide, urea, digested food and hormones around the body. White blood cells protect the body: phagocytes engulf pathogens and lymphocytes make antibodies or antitoxins.

  • plasma transports dissolved substances such as urea or carbon dioxide (1)
  • plasma also carries digested food, hormones or heat (1)
  • phagocytes engulf and digest pathogens (1)
  • lymphocytes make antibodies or antitoxins (1)

Common mistakes

  1. Saying red blood cells have a nucleus

    Mature red blood cells have no nucleus.

  2. Saying platelets are whole cells

    Platelets are fragments of cells with no nucleus.

  3. Saying plasma carries oxygen

    Oxygen is carried by haemoglobin in the red blood cells.

  4. Mixing up phagocytes and lymphocytes

    Phagocytes engulf pathogens. Lymphocytes make antibodies.

Questions students ask

Is Blood on the Foundation or Higher tier?

Blood is on both Foundation and Higher papers for GCSE Combined Science Biology, aimed at around grade 4.

What is a common mistake on Blood?

Saying red blood cells have a nucleus. Mature red blood cells have no nucleus.

Where are the answers to the Blood questions?

Open Show answer under each question on this page. The questions are Yumio practice questions, not past exam questions.

Related Biology topics

More on Blood

See how the papers are set: AQA Combined Science papers and Edexcel Combined Science papers.

Practise Blood free

Start free

Yumio is not affiliated with, endorsed by or connected to AQA, Pearson Edexcel or any other exam board.

Next topicPractise free