Blood is the red liquid that moves around your body. It is a tissue, which means a group of different cells and parts working together. It has four parts: plasma, red blood cells, white blood cells and platelets.
It matters because blood is the body's delivery and defence system. It takes oxygen and food to every cell, carries waste away, and helps to fight disease. Without it your cells would stop working.
By the end you will be able to name the four parts and say what each one does. You will also explain how red blood cells are built to carry oxygen.
Plasma
Plasma is the pale yellow liquid part of blood. Most of it is water. The other three parts are carried along in it, and so are many dissolved substances.
Think of plasma as the road that all the deliveries travel on. It carries digested food, such as glucose, from the gut to the cells. It carries carbon dioxide from the organs to the lungs. It carries urea, a waste made in the liver, to the kidneys.
Plasma also carries hormones, which are chemical messages, and it spreads heat around the body.
Red blood cells and haemoglobin
Red blood cells carry oxygen from the lungs to every cell in the body. Cells need oxygen to release energy from food.
Each red blood cell is full of haemoglobin. This is a red protein that joins with oxygen in the lungs to make oxyhaemoglobin. Think of haemoglobin as a tiny delivery van that picks up oxygen.
In the body tissues the haemoglobin lets go of the oxygen, and the oxygen passes into the cells. Haemoglobin is what makes blood look red.
How red blood cells are adapted
An adaptation is a feature that helps a cell do its job. Red blood cells have no nucleus. The nucleus is the part of a cell that holds its genes. Leaving it out makes more room for haemoglobin.
Each cell is a biconcave disc, which means it is dented in on both sides. This gives it a large surface area, so oxygen can get in and out quickly.
The cells are also small and flexible. This lets them squeeze through capillaries, which are the narrowest blood vessels.
White blood cells and phagocytes
White blood cells are part of the immune system, which defends the body. They fight pathogens. A pathogen is a microorganism that causes disease, such as a harmful bacterium or virus.
Some white blood cells are phagocytes. A phagocyte engulfs a pathogen, which means it wraps around it and takes it in. It then digests the pathogen and destroys it.
Unlike red blood cells, white blood cells have a nucleus. You have far fewer of them than red blood cells.
Antibodies and antitoxins
Other white blood cells are lymphocytes. They make antibodies, which are chemicals that destroy one particular kind of pathogen. Some also make antitoxins. These neutralise the poisons that pathogens release.
A football team is a helpful picture. Phagocytes are the defenders who tackle anything that should not be on the pitch. Lymphocytes are the planners, making antibodies aimed at one particular attacker.
When you have an infection, your body makes more white blood cells to fight it.
Platelets
Platelets are small fragments of cells. They have no nucleus, so they are not whole cells. Their job is to help the blood to clot.
To clot means to change from a runny liquid into a thick, sticky seal. When you cut yourself, platelets gather at the wound and a clot forms. The clot then dries into a scab.
The scab stops blood escaping and keeps microbes out while the skin heals. Think of it as a plaster that your body makes for itself. Without platelets, even a small cut would keep bleeding.
Recap
Blood has four parts: plasma, red blood cells, white blood cells and platelets.
Plasma is the liquid. It carries digested food, carbon dioxide, urea, hormones and heat.
Red blood cells carry oxygen using haemoglobin. They have no nucleus and are biconcave.
White blood cells fight pathogens. Platelets help the blood to clot.
Key points
Blood: plasma, red cells, white cells and platelets.
Plasma carries carbon dioxide, urea, digested food, hormones and heat.
Red cells: haemoglobin, biconcave, no nucleus.
White cells fight pathogens. Platelets clot blood.
Worked examples
Example 1
Name the red substance in red blood cells that carries oxygen.
Red blood cells carry oxygen.
The protein that joins to oxygen is in the cell.
It is haemoglobin.
Answer: haemoglobin
Common slips
Slip: plasma Plasma is the liquid part of the blood.
Slip: platelets Platelets help blood to clot.
Slip: chlorophyll Chlorophyll is green and found in plants.
Example 2
Give two ways in which a red blood cell is adapted to carry oxygen.
It has no nucleus, so there is more room for haemoglobin.
It is a biconcave disc, which gives a large surface area.
Haemoglobin joins with oxygen to carry it.
Answer: no nucleus and a biconcave shape
Common slips
Slip: It has a large nucleus. Red blood cells have no nucleus.
Slip: It has a cell wall. Animal cells such as red blood cells have no cell wall.
Slip: It is round and flat so it clots. Clotting is the job of platelets.
Example 3
A person has a cut. Describe the roles of platelets and white blood cells in the body’s response.
Platelets cause the blood to clot, forming a scab that stops blood loss.
The scab keeps pathogens out.
White blood cells inside engulf pathogens or make antibodies against them.
Answer: Platelets clot the blood to seal the cut and white blood cells engulf pathogens or make antibodies
Common slips
Slip: Platelets kill the pathogens. Platelets clot the blood. White blood cells attack pathogens.
Slip: White blood cells make the scab. The scab is made by platelets.
Slip: Red blood cells heal the cut. They carry oxygen. They do not seal wounds.
Questions and answers
Blood practice questions for GCSE Combined Science Biology. Try each one, then open the answer. Easy questions come first.
Question 1 Easy
Name the liquid part of blood.
Show answer
Answer: plasma
It carries the cells and dissolved substances.
It is plasma.
Question 2 Easy
Which blood cells carry oxygen?
Show answer
Answer: red blood cells
They contain haemoglobin.
They are red blood cells.
Question 3 Easy
Which part of blood helps it to clot?
Show answer
Answer: platelets
They seal wounds.
They are platelets.
Question 4 Easy
Name the type of cell that makes antibodies.
Show answer
Answer: white blood cell
Antibodies are part of the immune system.
White blood cells make them.
Question 5 Easy
Is plasma a solid, a liquid or a gas?
Show answer
Answer: liquid
Plasma is the part that the cells float in.
It is a liquid.
Question 6 Easy
What name is given to microorganisms that cause disease?
Show answer
Answer: pathogens
White blood cells fight these.
They are pathogens.
Question 7 Medium
Which red protein carries oxygen in the blood?
Show answer
Answer: haemoglobin
It is found in red blood cells.
It is haemoglobin.
Question 8 Medium
Name the white blood cells that engulf pathogens.
Show answer
Answer: phagocytes
They take in and digest pathogens.
They are phagocytes.
Exam-style questions
Longer questions in the style of a written paper, with the marking points. These are Yumio practice questions.
Exam-style question 14 marks
(a) Describe the function of platelets. [1 mark] (b) Explain how the structure of a red blood cell helps it to carry oxygen. [3 marks]
Show answer and marking points
Answer: (a) they help the blood to clot (b) haemoglobin joins with oxygen, no nucleus gives more room for haemoglobin, and the biconcave shape gives a large surface area
(a) help the blood to clot (1)
(b) contains haemoglobin, which joins with oxygen (1)
(b) no nucleus, so more room for haemoglobin (1)
(b) biconcave shape gives a large surface area (1)
Exam-style question 24 marks
Explain the roles of plasma and white blood cells in the blood. [4 marks]
Show answer and marking points
Answer: Plasma transports carbon dioxide, urea, digested food and hormones around the body. White blood cells protect the body: phagocytes engulf pathogens and lymphocytes make antibodies or antitoxins.
plasma transports dissolved substances such as urea or carbon dioxide (1)
plasma also carries digested food, hormones or heat (1)
phagocytes engulf and digest pathogens (1)
lymphocytes make antibodies or antitoxins (1)
Common mistakes
Saying red blood cells have a nucleus
Mature red blood cells have no nucleus.
Saying platelets are whole cells
Platelets are fragments of cells with no nucleus.
Saying plasma carries oxygen
Oxygen is carried by haemoglobin in the red blood cells.
Mixing up phagocytes and lymphocytes
Phagocytes engulf pathogens. Lymphocytes make antibodies.
Questions students ask
Is Blood on the Foundation or Higher tier?
Blood is on both Foundation and Higher papers for GCSE Combined Science Biology, aimed at around grade 4.
What is a common mistake on Blood?
Saying red blood cells have a nucleus. Mature red blood cells have no nucleus.
Where are the answers to the Blood questions?
Open Show answer under each question on this page. The questions are Yumio practice questions, not past exam questions.